Download From DNA to Diversity: Molecular Genetics and the Evolution by Sean B. Carroll, Jennifer Grenier, Scott Weatherbee PDF

April 5, 2017 | Evolution | By admin | 0 Comments

By Sean B. Carroll, Jennifer Grenier, Scott Weatherbee

Publish 12 months note: First released in 2004 (first edition)

In this landmark paintings, the writer workforce led by means of Dr. Sean Carroll offers the final rules of the genetic foundation of morphological swap via a synthesis of evolutionary biology with genetics and embryology. during this widely revised moment variation, the authors delve into the most recent discoveries, incorporating new assurance of comparative genomics, molecular evolution of regulatory proteins and components, and microevolution of animal improvement.

• An obtainable textual content, targeting the main recognized genes, developmental procedures and taxa.
• Builds logically from developmental genetics and regulatory mechanisms to evolution at diverse genetic morphological levels.
• provides significant insights from fresh genome experiences, new evo-devo biology examine findings, and a brand new bankruptcy on types of edition and divergence between heavily comparable species.
• offers in-depth specialise in key techniques via well-developed case studies.
• positive aspects transparent, 4-color illustrations and pictures, bankruptcy summaries, references and a glossary.
• provides the learn of Dr. Carroll, a pioneer within the box and the earlier president of the Society for Developmental Biology.

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Extra info for From DNA to Diversity: Molecular Genetics and the Evolution of Animal Design (2nd Edition)

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11a). The function of the engrailed gene is best understood in the embryo and in the developing wing, where it acts to determine posterior identity. Mutations in this gene cause posterior cells to develop as anterior cells but with reversed segmental polarity, resulting in mirror-image duplications of anterior tissue. The engrailed gene encodes member of a distinct class of homeodomain-containing transcription factors. A second compartmental selector gene, apterous (ap), subdivides the developing wing imaginal disc into dorsal and ventral compartments (Fig.

Zygotic genes are expressed at different positions along the dorsoventral axis with (b) snail expression in the most ventral cells, (c) sog expression in lateral cells, and (d) zen expression in the most dorsal cells. Source: Photographs courtesy of Michael Levine. processes such as embryonic axis formation and segmentation are organized by regulating gene expression in discrete regions and cell populations of the embryo. The transcription factors found in the Drosophila toolkit include representatives of most of the known families of sequence-specific DNA-binding proteins.

The segment polarity genes are expressed in each segment, in 14 or 15 transverse stripes (Fig. 17c). 17 Expression of segmentation genes Drosophila embryos stained with antibodies specific for the (a) Krüppel gap protein, (b) Hairy pair-rule protein, and (c) Engrailed segment polarity protein. Each protein is localized to nuclei in regions of the embryo that are affected by mutations in the respective genes. Source: Photographs by James Langeland. domains along the dorsoventral axis that correspond to regions of the embryo that give rise to elements such as the mesoderm, neuroectoderm (the part of the ectoderm from which the ventral nervous system develops), and amnioserosa (a dorsal sheet of extraembryonic cells) (Fig.

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