By Isabelle Queinnec, Sophie Tarbouriech, Germain Garcia, Silviu-Iulian Niculescu
Creating a few hyperlinks among keep an eye on suggestions and biology modeling groups in keeping with similarities in modeling, staring at and perceiving alive buildings, and interpreting interconnections among organic constructions and subsystems was once the most goal of this quantity.
In this context, biology platforms want acceptable research instruments as a result of their constitution and hierarchy, complexity and setting interference, and we think that those features could generate attention-grabbing examine subject matters on top of things region. certainly, numerous works, elevating the aptitude impression of keep an eye on advancements to deliver a few starting of solutions within the context of organic structures, were released within the fresh years.
The suggestion of this publication used to be conceived within the context pointed out above with the target to aid in claiming some of the difficulties for keep watch over researchers, beginning discussions and starting interactive debates among the keep watch over and biology groups, and, ultimately, to alert graduate scholars to the various attention-grabbing rules on the frontier among keep an eye on suggestions concept and biology.
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Additional info for Biology and control theory: current challenges
The biological meaning of follicular development is to free fertilizable oocytes at the time of ovulation. The selection of ovulatory follicles in mammal ovaries is an FSH dependent selection process. In this paper, we design a multiscale model of follicular development, where selection arises from the feedback between the ovaries and the pituitary gland and appeals to control theory concepts. Each ovarian follicle is characterized by a 2D density function giving an age and maturity-structured description of its cell population.
Eur. J. , 30:2704–2712, 2000. 19. JF. Delfraissy. Prise en charge des personnes infectées par le VIH : Recommandations du groupe d’experts. Médecine Science, Paris, ﬂammarion edition, 2004. shtml. 20. S. Dept. Health and Human Services. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents, May 2006. gov/guidelines. 21. I. T. Prud’homme et al. 0 viral load assays: a Canadian evaluation. Journal of Clinical Virology, 11:189–202, 1998. 22. A. Berger et al. 0 assays for quantitation of HIV-1 RNA in plasma samples.
These results open new perspectives in this domain. For instance, the application of the identiﬁed models for the optimal control of the infection kinetics becomes possible. It will involve control theories of non-linear systems: the reader can refer to [31, 32, 33, 2, 17, 34] for details on application of control theories to some models of the HIV/AIDS infection. References 1. A. M. Jeﬀrey. A control theoretic approach to HIV/AIDS drug dosage desing and timing the initiation of therapy. PhD thesis, University of Preotria, South Africa, July 2006.